Phospho-NuMA (Thr2055) Antibody
货号：
14951S 基本售价：
3980.0 元 规格：
-
产品信息
概述| 货号 | 14951S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | The nuclear mitotic apparatus protein (NuMA) is a coiled coil protein involved in the formation and maintenance of the mitotic spindle. NuMA plays a role in chromatin organization during interphase, which influences mammary epithelial differentiation (1,2). During apoptosis, carboxy-terminal cleavage of NuMA may amplify signaling in the cell death pathway (2). NuMA is phosphorylated at numerous sites, with phosphorylation at Ser395 occurring in an ATM/ATR-dependent manner in response to DNA damage (3,4). |
| 存放说明 | -20C |
| 计算分子量 | 238 |
参考图片Western blot analysis of HT-29 cell extracts, untreated (-) or treated with thymidine (2 mM, 16 hr) followed by Nocodazole #2190 (10 nM, 24 hr; +), using Phospho-NuMA (Thr2055) Antibody (upper), NuMA (D49H4) Rabbit mAb #8967 (middle), and α-Actinin (D6F6) XP® Rabbit mAb #6487 (lower). |
