| 货号 | 2049S |
| 反应种属 | Human/Mouse/Rat/Monkey |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | Tug Antibody detects endogenous levels of total Tug protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 灵敏度 | Endogenous |
| 背景 | Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma (1) and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation (2). Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution (3). |
| 存放说明 | -20C |
| 计算分子量 | 70-75 |
| 参考文献 | 1 . Ladanyi, M. et al. (2001) Oncogene 20, 48-57. 2 . Bogan, J.S. et al. (2003) Nature 425, 727-33. 3 . Yu, C. et al. (2007) J Biol Chem 282, 7710-22. |
Western blot analysis of extracts from various cell lines using Tug Antibody. 对多个细胞系抽提液使用Tug Antibody进行Western blot分析。 |
