货号 | 4456S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | Nna1 Antibody detects endogenous levels of total Nna1 protein. |
使用方法 | WB(1:1000) IP (1:50) |
供应商 | CST |
背景 | Nervous system nuclear protein induced by axotomy 1 (Nna1, AGTPBP1 or cytosolic carboxypeptidase-1) is related to zinc carboxypeptidases and contains an ATP/GTP binding motif, a basic and a bipartite nuclear localization signal. Nna1 expression is rapidly induced in motor neurons following axotomy and down-regulated following reinnervation, which is consistent with abundant Nna1 expression in differentiating neurons and the absence of Nna1 in CNS proliferative zones (1). Furthermore, Purkinje cell degeneration is characterized by adult onset neurodegeneration resulting from Nna1 gene mutations, implicating Nna1 in mechanisms common to degeneration and regeneration (2). |
存放说明 | -20C |
计算分子量 | 145 |
Western blot analysis of extracts from fetal and adult rat brain using Nna1 Antibody. Western blot分析胚胎大鼠和成年大鼠大脑提取物,使用的抗体是Nna1 Antibody 兔多抗。 |