MOB1 Antibody
货号：
3863S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 3863S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | MOB1 Antibody detects endogenous levels of total MOB1 protein (MOB1α and MOB1β). |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy (1). Its Drosophila and mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo Signaling Pathway, which has critical roles in controlling organ size, homeostasis and cancer development (2-5). MOB1 binds to members of the nuclear Dbf2-related kinases, such as LATS1 and 2, and NDR1 and 2, and stimulates their kinase activity (6-8). This binding is promoted by the phosphorylation of MOB1 at several Threonine residues by MST1 and/or MST2 (9,10). There are two MOB1 proteins in humans, MOB1α and MOB1β that are encoded by two different genes but have 96.3% identity (10). |
| 存放说明 | -20C |
| 计算分子量 | 25 |
参考图片Western blot analysis of extracts from various cell lines using MOB1 Antibody.使用MOB1抗体对多种细胞提取物进行western blot分析。 |
