Maspin (L250) Antibody
货号：
9119S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 9119S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | Maspin (Q260) Antibody detects endogenous levels of total maspin protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Maspin (SERPINB5) was discovered as a mammary tumor suppressor that is expressed in normal mammary epithelium but lost in most breast cancer cell lines (1). While maspin is related to the serpin family of serine protease inhibitors, it may not function as a protease inhibitor (2). It plays an essential role in embryonic development through critical roles in cell adhesion (3). While the precise mechanism of maspin signaling is unclear (4), the tumor suppressing activity of maspin has been attributed to its ability to inhibit cell invasion/metastasis (5,6) and angiogenesis (7), while promoting apoptosis (8). Nuclear translocation of active IKKα has been shown to repress maspin transcription and promote prostate cancer metastasis (9). |
| 存放说明 | -20C |
| 计算分子量 | 40 |
参考图片Western blot analysis of extracts from HT-1080, HT-29 and COLO-201 cell lines using Maspin (L250) Antibody. 用 Maspin (L250) Antibody经Western blot 分析 HT-1080、HT-29 和COLO-201细胞系的细胞提取液 。 |
