MAML2 Antibody
货号:
4618S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 4618S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | MAML2 Antibody detects endogenous levels of total MAML2 protein. It does not cross-react with MAML1 and MAML3. |
使用方法 | WB(1:1000) IP (1:50) |
性能供应商 | CST |
背景 | Mastermind-like (MAML) family of proteins are homologs of Drosophila Mastermind. The family is composed of three members in mammals: MAML1, MAML2, and MAML3 (1,2). MAML complexes with the intracellular domain of Notch (ICN) and the transcription factor CSL (RBP-Jκ) to regulate Notch target gene expression (3-5). MAML1 also interacts with MEF2C (myocyte enhancer factor 2C) to regulate myogenesis (6). MAML2 is frequently found to be fused with Mucoepidermoid carcinoma translocated gene 1 (MECT1, also know as WAMTP1 or TORC1) in patients with mucoepidermoid carcinomas and Warthins tumors (7). |
存放说明 | -20C |
计算分子量 | 160 |
参考图片Western blot analysis of total cell lysates from 293, NIH/3T3 and A10 cells, using MAML2 antibody.使用MAML2抗体对293, NIH/3T3和A10全细胞提取物进行western blot分析。 |