HS1 Antibody (Rodent Specific)
货号:
4557S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 4557S |
反应种属 | Mouse/Rat |
来源宿主 | Rabbit |
应用 | W/IP |
目标/特异性 | HS1 Antibody (Rodent Specific) detects endogenous levels of total HS1 protein. This antibody does not recognize human HS1 protein. HS1 has a calculated size of 54 kDa, but has an apparent molecular weight of 80 kDa on SDS-PAGE gels. |
使用方法 | WB(1:1000) IP (1:25) |
性能供应商 | CST |
背景 | HS1 (HCLS1, LckBP1, p75) is a protein kinase substrate that is expressed only in tissues and cells of hematopoietic origin (1,2). HS1 contains four cortactin repeats and a single SH3 domain (2). This intracellular protein is phosphorylated following immune receptor activation, which promotes recruitment of HS1 to the immune synapse (3-5). Phosphorylation of HS1 is required to regulate actin dynamics and provide docking sites for many other signaling molecules, such as Vav1 and PLCγ1 (6). HS1 also plays an important role in platelet activation (7). |
存放说明 | -20C |
计算分子量 | 80 |
参考图片Western blot analysis of cell extracts from BaF3 and rat thymocytes using HS1 Antibody (Rodent Specific).Western免疫印迹。用HS1 Antibody (Rodent Specific)研究BaF3细胞和大鼠胸腺细胞的细胞提取液。 |