| 货号 | 5269S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | HMGA2 Antibody detects endogenous levels of total HMGA2 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | HMGA2 belongs to the family of high mobility group with AT-hook DNA binding domain. HMGA proteins are considered architectural transcription factors; they do not have direct transcriptional activation capacity, but instead regulate gene expression by changing DNA conformation through binding to AT-rich regions in the DNA, and/or direct interaction with other transcription factors (1,2). HMGA2 is abundantly and ubiquitously expressed and plays a crucial role during embryonic development (3). HMGA2 promotes stem cell self-renewal and decreases in its expression are associated with stem cell aging (4-7). Expression levels of HMGA2 are very low in normal adult tissues, but its overexpression or rearrangement is associated with many types of cancer (8-11). |
| 存放说明 | -20C |
| 计算分子量 | 18 |
Western blot analysis of extracts from various cell lines using HMGA2 Antibody. 使用HMGA2 Antibody，免疫印迹(Western blot)分析不同细胞中HMGA2的蛋白水平。 |
