Hip Antibody
货号:
2723S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 2723S |
反应种属 | Human/Mouse/Rat/Monkey |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Hip Antibody detects endogenous levels of total Hip protein. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8). |
存放说明 | -20C |
计算分子量 | 48 |
参考图片Western blot analysis of extracts from various cell types using Hip Antibody. 对多个细胞系抽提液使用 Hip Antibody进行Western blot分析。 |