| 货号 | 2320S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IF-IC |
| 目标/特异性 | AP-2γ Antibody detects endogenous levels of total AP-2γ protein. |
| 使用方法 | WB(1:1000) IF-IC (1:400) |
| 供应商 | CST |
| 背景 | Activator protein 2γ (AP-2γ) is a member of the developmentally-regulated transcription factor activator protein 2 family (1). Overexpression of p53 in human breast cancer cells increases AP-2γ mRNA and protein (2). In addition, p53 binds to the AP-2γ promoter, suggesting that AP-2γ is a target of p53. AP-2γ therefore may contribute to p53-mediated growth inhibition (2). Studies also found that AP-2γ increases p21 mRNA and protein levels and induces cell-cycle arrest in G1 phase (3). Overexpression of AP-2γ inhibits the growth of human breast cancer cells (3). Taken together, these findings suggest that AP-2γ functions as a tumor suppressor (3). |
| 存放说明 | -20C |
| 计算分子量 | 49 |
Western blot analysis of extracts from several cell lines, using AP-2γ Antibody. Western免疫印迹。用AP-2γ Antibody研究各种细胞系的细胞提取液。 | |
Confocal immunofluorescent analysis of MCF-7 cells, using AP-2gamma Antibody (green). Actin filaments have been labeled with Alexa Fluor® 555 phalloidin (red). 共聚焦免疫荧光分析MCF-7细胞，所用抗体为AP-2gamma Antibody (绿色)。肌动蛋白微丝用Alexa Fluor® 555 phalloidin (红色)标记。 |
