| 货号 | MAB2664-SP |
| 别名 | CD305 antigen; CD305; CD305leukocyte-associated Ig-like receptor 1; hLAIR1; LAIR-1; leukocyte-associated immunoglobulin-like receptor 1 | 全称 | Leukocyte-associated Ig-like Receptor 1 |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
| 目标/特异性 | Detects human LAIR1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human LAIR2 or recombinant mouse LAIR1 is observed. |
| 使用方法 | Western Blot: 1 µg/mL Flow Cytometry: 2.5 µg/106cells |
| 来源 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3903 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human LAIR1 isoform 1 Gln22-His163 Accession # Q6GTX8 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | LAIR1 is an inhibitory receptor belonging to the Ig superfamily. It isa type I transmembrane protein with one extracellular Ig-like domainand two cytoplasmic ITIMs. Four LAIR1 splice variants exist. LAIR1b hasa 17 aa deletion outside the Ig loop in the extracellular domain. Itdiffers from LAIR1c by one aa residue. LAIR1d has a 77 aa truncation inthe cytoplasmic domain. LAIR1 is expressed on NK cells, T cells, Bcells, monocytes, dendritic cells and most thymocytes. Theextracellular domain of human LAIR1 shares 40% aa identity with that ofthe mouse protein. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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