| 货号 | MAB7441-SP |
| 别名 | MGC129934; MGC129935; TL1A; TL1Vascular endothelial cell growth inhibitor; TNF superfamily ligand TL1A; TNFSF15; tumor necrosis factor (ligand) superfamily, member 15; tumor necrosis factor ligand superfamily member 15; vascular endothelial growth inhibitor-192A; VEGI; VEGI192A; VEGITNF ligand-related molecule 1 | 全称 | TNF-like 1 |
| 反应种属 | Human/Mouse |
| 应用 | Western Blot(1 µg/mL) |
| 目标/特异性 | Detects mouse TL1A/TNFSF15 in direct ELISAs and Western blots. Shows 100% cross-reactivity with recombinant human TL1A. |
| 使用方法 | Western Blot: 1 µg/mL Neutralization: Reichwald, K. et al. (2014) PLoS ONE. 9:e85793. Reichwald, K. et al. (2014) PLoS ONE. 9:e105627. |
| 来源 | Monoclonal Rat IgG1 Clone # 293327 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9966 (Human); 326623 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. TL1A induces TCR independent IL-6 and TNF-alpha production and growth of PLZF(+) leukocytes. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | E. coli-derived recombinant mouse TL1A/TNFSF15 Ile94-Leu270 Accession # NP_796345.3 |
| 生物活性 | Human, Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | TL1A is a type II transmembrane protein belonging to the TNFsuperfamily and has been designated TNFSF15. It is expressedpredominantly in endothelial cells, and its expression is inducible byTNF-alpha and IL-1 alpha. TL1A binds with high affinity to DR3/TNFRSF25 onactivated T cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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