| 货号 | MAB13441-SP |
| 别名 | APS seminin; EC 3.4.21; EC 3.4.21.77; Gamma-seminoprotein; hK3; kallikrein 3, (prostate specific antigen); Kallikrein-3; kallikrein-related peptidase 3; KLK2A1; KLK3; P-30 antigen; prostate specific antigen; prostate-specific antigen; PSA semenogelase; PSA; Semenogelase; Seminin |
| 反应种属 | Human |
| 应用 | Neutralization |
| 目标/特异性 | Detects human Kallikrein 3/PSA in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Factor X, rhHGF-A, rhKLK-4, -5, -8, -11, or rhThrombin is observed. |
| 使用方法 | Neutralization: Measured by its ability to neutralize Recombinant Human Kallikrein 3/PSA (10 µg/mL, Catalog # 1344-SE) cleavage of the fluorogenic peptide substrate Suc-RPY-pNA (1 mM). The Neutralization Dose (ND50) is typically 21 µg/mL. |
| 来源 | Monoclonal Mouse IgG2B Clone # 181827 |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 354 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Transient induction of ING4 by Myc drives prostate epithelial cell differentiation and its disruption drives prostate tumorigenesis. | |
| 纯化方式 | Protein A or G purified from hybridoma culture supernatant |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Kallikrein 3/PSA Pro19-Pro261 Accession # NP_001639 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.5 mg/mL in sterile PBS. |
| 背景 | Kallikrein 3 is a member of the Kallikrein family of serine proteases. It is also known as PSA (prostate-specific antigen) and is used in prostate cancer diagnosis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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