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货号： bsm-30067M-PE-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-30067M-PE-Bio
- 英文名称
- Anti-human CD5-PE/Biotin
- 中文名称
- 生物素标记的PE标记小鼠抗人CD5单克隆抗体
- 别 名
- T-cell surface glycoprotein CD5; Lymphocyte antigen 1; Ly-1; Lyt-1; CD5; CD5 antigen; CD 5; CD5 molecule; CD5 antigen (p56 62); CD5_HUMAN; LEU 1; LEU1; Ly12; LyA; Lymphocyte Antigen CD5; Lymphocyte antigen T1/Leu 1; Lymphocyte antigen T1/Leu-1; Lymphocyte glycoprotein T1/Leu1; OTTHUMP00000236973; p56 62; T1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 干细胞 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Function:
May act as a receptor in regulating T-cell proliferation.
Subunit:
Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Post-translational modifications:
Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.
Similarity:
Contains 3 SRCR domains.
Database links:Entrez Gene: 921 Human
Omim: 153340 Human
SwissProt: P06127 Human
Unigene: 58685 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.