CD146 (LSEC)-APC, rat, REA697, 100 tests
货号:
130-111-395 基本售价:
询价 规格:
-
产品信息
概述货号 | 130-111-395 |
描述 | Clone REA697 recognizes the rat CD146 (LSEC) antigen, also known as Gicerin, MCAM, MUC18, or MEL-CAM. CD146 is a putative cell adhesion molecule of an immunoglobulin (Ig) superfamily which shows homophilic and heterophilic binding activities with two isoforms: S-gicerin, which has small cytoplasmic domain and the same extracellular domain as l-gicerin, shows stronger cell adhesion activity. CD146 is expressed on endothelial cells and a variety of tumor cells and is involved in cell adhesion and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. In rat, neurite promotion activity of CD146 from hippocampal neurons is reported.Additional information: Clone REA697 displays negligible binding to Fc receptors. |
别名 | MCAM, 1-gicerin, MUC18, S-endo, s-gicerin, Endo-CAM, Mel-CAM |
克隆号 | REA697 |
同种亚型 | recombinant human IgG1 |