CD8a-PE-Vio770, rat
货号：
130-108-913 基本售价：
询价 规格：
-
产品信息
概述| 货号 | 130-108-913 |
| 描述 | Clone REA437 recognizes the rat CD8a antigen, a single-pass type I membrane protein, which is also known as OX-8. CD8 acts as a co-receptor for the T cell receptor and recognizes antigen displayed by an antigen presenting cell in the context of class I MHC molecules. CD8a is expressed as a heterodimer with CD8b on T cell receptor (TCR) α/β and TCR γ/δ expressing, cytotoxic T cells, and on most thymocytes. As a homodimer of two CD8a chains the CD8 antigen is expressed on most NK cells, a major fraction of intestinal intraepithelial lymphocytes, some activated CD4+CD8+ T cells and CD8+ T cells from athymic rats. CD8a is also expressed by a T cell subset with regulatory functions.Additional information: Clone REA437 displays negligible binding to Fc receptors. |
| 别名 | OX-8, Lyt2, Ly-2 |
| 克隆号 | REA437 |
| 同种亚型 | recombinant human IgG1 |
