CD86-APC, rat 60 tests
货号：
130-109-177 基本售价：
询价 规格：
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产品信息
概述| 货号 | 130-109-177 |
| 描述 | Clone 24F recognizes the rat antigen CD86, also known as B7-2, which is a member of the B7 family of costimulatory molecules. In addition to CD80 (B7-1) , CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). It is expressed by germinal center B cells and weakly expressed on antigen presenting cells, such as macrophages and dendritic cells. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. CD86 plays a critical role in the early events of T cell activation and costimulation of naive T cells as well as autoantibody and Tʜ2-mediated Ig production. |
| 别名 | B7-2, B70 |
| 克隆号 | 24F |
| 同种亚型 | mouse IgG1κ |
