CD200-Biotin, rat 60 tests
货号：
130-108-124 基本售价：
询价 规格：
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产品信息
概述| 货号 | 130-108-124 |
| 描述 | Clone REA532 recognizes the rat CD200 antigen, which is a transmembrane glycoprotein containing two extracellular immunoglobulin domains and lacks intracellular signaling motifs or docking sites for adapter signaling molecules. CD200, also known as MRC OX-2 antigen, is expressed on a variety of tissues, including the nervous system, activated T cells, B cells, dendritic cells in lymphatic follicles, cells of glomeruli and ovarian degenerating follicles, and vascular endothelium. It is also distributed at the epithelium-derived tissues such as the thymus, retinas, and hair follicles. CD200 interacts with CD200R, an immunoglobulin superfamily inhibitory receptor expressed primarily on myeloid/monocyte lineage cells, and has a suppressive effect on T cell–mediated immune response. Additional information: Clone REA532 displays negligible binding to Fc receptors. |
| 别名 | Cspmo2, MRCOX2, Mox2 |
| 克隆号 | REA532 |
| 同种亚型 | recombinant human IgG1 |
