CD134-Biotin, rat 60 tests
货号:
130-108-211 基本售价:
询价 规格:
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产品信息
概述货号 | 130-108-211 |
描述 | Clone REA540 recognizes the rat CD134 (OX40) antigen, a 50 kDa glycoprotein which is a member of the TNFR superfamily. It contains a typical signal sequence and a single putative transmembrane sequence of 25 predominantly hydrophobic amino acids giving an extracellular domain of 191 amino acids and a cytoplasmic domain of 36 amino acids. The expression of CD134 is restricted to activated rat CD4+ T cells and is up-regulated within hours after activation. CD134 and its ligand CD252 (CD134L, OX40L), which is expressed on activated T and B lymphocytes and also a member of the tumor necrosis factor receptor superfamily, were suggested to mediate the interaction between T cells and B cells.Additional information: Clone REA540 displays negligible binding to Fc receptors. |
别名 | TNFRSF4, OX-40, Txgp1, MRC OX40 |
克隆号 | REA540 |
同种亚型 | recombinant human IgG1 |