EpCAM (VU1D9) Mouse mAb (Alexa Fluor® 555 Conjugate)
货号:
5488S 基本售价:
4060.0 元 规格:
-
产品信息
概述货号 | 5488S |
描述 | This Cell Signaling Technology antibody is conjugated to Alexa Fluor® 555 fluorescent dye and tested in-house for immunofluorescent analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated EpCAM (VU1D9) Mouse mAb #2929. |
反应种属 | Human |
来源宿主 | Mouse |
应用 | IF-IC |
目标/特异性 | EpCAM (VU1D9) Mouse mAb (Alexa Fluor® 555 Conjugate) detects endogenous levels of total EpCAM protein. |
使用方法 | IF-IC(1:50) |
性能供应商 | CST |
标记 | Alexa Fluor 555 |
背景 | Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). One of the first tumor-associated antigens discovered, EpCAM has long been a marker of epithelial and tumor tissue. Because of its high expression in cancer, EpCAM has become a therapeutic target for human solid tumors of epithelial lineage (reviewed in 2,3). |
存放说明 | 4C |
参考图片Confocal immunofluorescent analysis of HT-29 cells (left) and HeLa cells (right) using EpCAM (VU1D9) Mouse mAb (Alexa Fluor® 555 Conjugate) (red). Blue pseudocolor= DRAQ5® #4084 (fluorescent DNA dye).使用EpCAM (VU1D9)鼠单抗(a Fluor® 555 标记)(红色)对HT-29细胞(左)和HeLa细胞(右)进行激光共聚焦荧光分析。蓝色假色=DRAQ5® #4084(DNA荧光染料)。 |