Oct-4A (C30A3) Rabbit mAb (Alexa Fluor® 555 Conjugate)
货号:
4439S 基本售价:
4060.0 元 规格:
-
产品信息
概述货号 | 4439S |
描述 | This Cell Signaling Technology antibody is conjugated to Alexa Fluor® 555 fluorescent dye and tested in-house for immunofluorescent analysis in human cells. This antibody is expected to exhibit the same species cross-reactivity as the unconjugated Oct-4A (C30A3) Rabbit mAb #2840。 |
反应种属 | Human/Mouse |
来源宿主 | Rabbit |
应用 | IF-IC |
使用方法 | IF-IC(1:50) |
性能供应商 | CST |
标记 | Alexa Fluor 555 |
背景 | Oct-4 (POU5F1) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells (1). A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation (2,3). Oct-4 is a useful germ cell tumor marker (4). Oct-4 exists as two splice variants, Oct-4A and Oct-4B (5). Recent studies have suggested that it is the Oct-4A isoform that has the ability to confer and sustain pluripotency and that Oct-4B may exist in some somatic, non-pluripotent cells (6,7). |
存放说明 | 4C |