Phospho-Jak2 (Tyr1007/1008) (C80C3) Rabbit mAb
货号:
3776S 基本售价:
3980.0 元 规格:
-
产品信息
概述货号 | 3776S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W |
目标/特异性 | Phospho-Jak2 (Tyr1007/1008) (C80C3) Rabbit mAb detects endogenous levels of Jak2 when phosphorylated at Tyr1007/1008. This antibody can also detect single phosphorylation at either 1007 or 1008. This antibody may cross-react with phospho-Jak1 and phospho-Tyk2. |
使用方法 | WB(1:1000) |
性能供应商 | CST |
背景 | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3 and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4) and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. |
存放说明 | -20C |
计算分子量 | 125 |
参考图片Western blot analysis of extracts from UT-7 and BaF3 cells, untreated or treated with GM-CSF or IL-3 (5 minutes), using Phospho-Jak2 (Tyr1007/1008) (C80C3) Rabbit mAb #3776 (top) or total Jak2 (D2E12) XP® Rabbit mAb #3230 (bottom).Western免疫印迹。用Phospho-Jak2 (Tyr1007/1008) (C80C3) Rabbit mAb #3776 (上图) 或 total Jak2 (D2E12) XP® Rabbit mAb #3230 (下图)研究未经处理的和经GM-CSF 或IL-3 (5 min)处理的UT-7 和BaF3 细胞的细胞提取液。 |