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货号： bsm-51433M-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-51433M-Bio
- 英文名称
- Anti-RPS6 (N-term)/Biotin
- 中文名称
- 生物素标记的小鼠抗S6核糖体蛋白单克隆抗体
- 别 名
- 40S ribosomal protein S6; Air8; DS6; Hemocytes enlarged; Hen; L(1)AIR8; Lethal (1) haemocytes enlarged; Lethal aberrant immune response 8; Lethal(1)abberant immune response[8]; Phosphoprotein NP33; Pp30; Ribosomal protein S6; RP S6; RPS 6; RpS6; RS6; RS6_HUMAN; S6; S6 Ribosomal Protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- 3D5
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- Recombinant human RPS6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Function:
May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
Post-translational modifications:
Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Phosphrylated at Ser-235 and Ser-236 by RPS6KA1 and RPS6KA3; phosphorylation at these sites facilitates the assembly of the preinitiation complex.
Similarity:
Belongs to the ribosomal protein S6e family.
Database links:Entrez Gene: 6194 Human
Entrez Gene: 20104 Mouse
Entrez Gene: 667739 Mouse
Entrez Gene: 29304 Rat
Omim: 180460 Human
SwissProt: P62753 Human
SwissProt: P62754 Mouse
SwissProt: P62755 Rat
Unigene: 408073 Human
Unigene: 379007 Mouse
Unigene: 425090 Mouse
Unigene: 34341 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.