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货号： bsm-51155M-Bio 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-51155M-Bio
- 英文名称
- Anti-FASN/Biotin
- 中文名称
- 生物素标记的小鼠抗脂肪酸合成酶单克隆抗体
- 别 名
- fatty acid synthase; FASN; FAS; FA Synthase 1; MGC14367; MGC15706; OA-519; Fatty acid synthase; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; Enoyl-[acyl-carrier-protein] reductase; Oleoyl-[acyl-carrier-protein] hydrolase; FAS_MHUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 免疫学 神经生物学 信号转导 合成与降解
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- 2C5
- 交叉反应
- Human, Mouse,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 274kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FASN
- 亚 型
- IgM
- 纯化方法
- affinity purified by Protein AGL
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
FASN (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis. FAS is a target for SREBP and is upregulated by LXR activation; it is also one of the accepted markers for insulin resistance, SREBP and LXR activation.
Function:
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Subunit:
Homodimer which is arranged in a head to tail fashion.
Subcellular Location:
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity:
Ubiquitous. Prominent expression in brain, lung, and liver.
Similarity:
Contains 1 acyl carrier domain.
Database links:Entrez Gene: 2194 Human
Entrez Gene: 14104 Mouse
Entrez Gene: 50671 Rat
Entrez Gene: 281152 Cow
Omim: 600212 Human
SwissProt: P12276 Chicken
SwissProt: Q71SP7 Cow
SwissProt: P49327 Human
SwissProt: P19096 Mouse
SwissProt: P12785 Rat
Unigene: 8951 Chicken
Unigene: 30099 Cow
Unigene: 83190 Human
Unigene: 236443 Mouse
Unigene: 9486 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.