| 货号 | 12731S |
| 反应种属 | Human/Mouse/Rat |
| 来源宿主 | Rabbit |
| 应用 | W/IP |
| 目标/特异性 | APBA2 (D8A6) Rabbit mAb recognizes endogenous levels of total APBA2 protein. |
| 使用方法 | WB(1:1000) IP (1:50) |
| 供应商 | CST |
| 背景 | Amyloid β A4 precursor protein-binding family A member 2 (APBA2) is a neuronal adaptor protein that interacts with the amyloid β precursor protein (APP) (1). The amyloid β-protein (Aβ) is the principal component of amyloid plaques, a pathological hallmark of Alzheimer’s disease (2). APBA2 has been shown to stabilize APP metabolism and suppress the secretion of Aβ (3). APBA2 mediates interaction between APP and the neural type I membrane protein Alcadein (Alc) by linking their cytoplasmic domains, thereby forming a tripartite complex of the three proteins in neurons (4). |
| 存放说明 | -20C |
| 计算分子量 | 135 |
Western blot analysis of extracts from mouse and rat brain using APBA2 (D8A6) Rabbit mAb. Western blot 检测小鼠和大鼠的大脑提取物，使用的抗体是 APBA2 (D8A6) Rabbit mAb兔单抗。 |
