ARP2 (D85D5) Rabbit mAb
货号：
5614S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 5614S |
| 反应种属 | Human/Mouse/Rat/Monkey/Bovine |
| 来源宿主 | Rabbit |
| 应用 | W |
| 目标/特异性 | ARP2 (D85D5) Rabbit mAb recognizes endogenous levels of total ARP2 protein. |
| 使用方法 | WB(1:1000) |
性能| 供应商 | CST |
| 背景 | Actin nucleation, the formation of new actin filaments from existing filaments, affects actin filament structure during cell motility, division, and intracellular trafficking. An important actin nucleation protein complex is the highly conserved ARP2/3 complex, consisting of ARP2, ARP3, and ARPC1-5. The ARP2/3 complex promotes branching of an existing actin filament and formation of a daughter filament following activation by nucleation-promoting factors, such as WASP/WAVE or cortactin (1). The formation of podosomes, small cellular projections that degrade the extracellular matrix, is enhanced by ARP2/3 complex action. ARP2/3 competes with caldesmon, an actin binding protein shown to negatively affect podosome formation (2). Along with N-WASP, the ARP2/3 complex regulates nuclear actin filament nucleation and controls actin polymerization during transcription (3). |
| 存放说明 | -20C |
| 计算分子量 | 44 |
参考图片Western blot analysis of extracts from various cell lines using ARP2 (D85D5) Rabbit mAb.使用ARP2 (D85D5)Rabbit mAb对多种细胞提取物进行western blot分析。 |
