DDC (D6N8N) Rabbit mAb
货号:
13561S 基本售价:
3360.0 元 规格:
-
产品信息
概述货号 | 13561S |
反应种属 | Human/Mouse/Rat |
来源宿主 | Rabbit |
应用 | W/IP |
使用方法 | WB(1:1000) IP (1:50) |
性能供应商 | CST |
背景 | L-DOPA decarboxylase (DDC) is a pyridoxal 5-phosphate (PLP)-dependent enzyme that catalyzes the decarboxylation of L-DOPA to dopamine (1) and L-5HTP to serotonin (2). By catalyzing the reaction to produce dopamine, DDC is involved in many important metabolic processes and plays a central role in the complex neuroendocrine-immune regulatory network (1). DDC is expressed in the central nervous system (3), but has also been detected in some peripheral organs such as the liver and adrenal gland, as well as leukocytes of rat and human (1). DDC is thought to be the sole enzyme responsible for the synthesis of the trace amines 2-phenylethylamine, p-tyramine, and tryptamine, which are considered to act as neuromodulators (2,4). DDC is also regarded as a general biomarker for neuroendocrine tumors (3). |
存放说明 | -20C |
计算分子量 | 48 |
参考图片Western blot analysis of extracts from PC-12 and KNRK cells using DDC (D6N8N) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower). |