| 货号 | 8138S |
| 反应种属 | Rat |
| 来源宿主 | Mouse |
| 应用 | W/IP/IF-F |
| 目标/特异性 | Insulin (L6B10) Mouse mAb recognizes endogenous levels of total insulin and proinsulin. |
| 使用方法 | WB(1:1000) IP (1:50) IF-F (1:800) |
| 供应商 | CST |
| 背景 | The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway (1). Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus (2). |
| 存放说明 | -20C |
| 计算分子量 | 6 |
Confocal immunofluorescent analysis of rat pancreas using Insulin (L6B10) Mouse mAb (green) and S6 Ribosomal Protein (5G10) Rabbit mAb #2217 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). 对大鼠胰腺使用Insulin (L6B10) Mouse mAb鼠单抗（绿色）和S6 Ribosomal Protein (5G10) Rabbit mAb兔单抗 #2217（红色）进行共聚焦免疫荧光分析。蓝色伪彩=DRAQ5?#4084(荧光DNA染料)。 | |
Western blot analysis of extracts from INS-1 cells using Insulin (L6B10) Mouse mAb. 对INS-1细胞使用Insulin (L6B10) Mouse mAb鼠单抗进行Western blot分析。 |
