| 货号 | 8827S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-IC |
| 目标/特异性 | Jak3 (D1H3) Rabbit mAb recognizes endogenous levels of total Jak3 protein. |
| 使用方法 | WB(1:1000) IP (1:100) IF-IC (1:200) |
| 供应商 | CST |
| 背景 | Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors (1). Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats (2), Shc (3), insulin receptor substrates (4), and focal adhesion kinase (FAK) (5), typically contain SH2 or other phospho-tyrosine-binding domains. |
| 存放说明 | -20C |
| 计算分子量 | 115 |
Confocal immunofluorescent analysis of KARPAS-299 cells (left) and A549 cells (right) using Jak3 (D1H3) Rabbit mAb (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).共聚焦免疫荧光分析KARPAS-299 细胞 (左图) 和A549 细胞(右图)，所用抗体为Jak3 (D1H3) Rabbit mAb (绿色)。Blue pseudocolor = DRAQ5® #4084 (DNA荧光染料)。 | |
Western blot analysis of extracts from various cell lines using Jak3 (D1H3) Rabbit mAb.Western免疫印迹。用Jak3 (D1H3) Rabbit mAb研究各种细胞的细胞提取液。 |
