货号 | 3389S |
反应种属 | Human/Mouse/Hamster/Monkey |
来源宿主 | Mouse |
应用 | W/IP/IHC-P/IF-IC |
目标/特异性 | LPP (8B3A11) Mouse mAb detects endogenous levels of total LPP protein. |
使用方法 | WB(1:1000) IP (1:50) IHC-P (1:100) IF-IC (1:100) |
供应商 | CST |
背景 | LIM-containing lipoma-preferred partner (LPP) belongs to the zyxin family, members of which include LIMD1, ajuba, trip6 and zyxin. Three LIM domains at the carboxy-terminus characterize this family of proteins. Zyxin family members associate with the actin cytoskeleton and are components of both the cell-cell junction adhesive complex and the integrin-mediated adhesive complex (1). They shuttle in and out of the nucleus where they may function in transcriptional activation (1). LPP binding partners at cell-cell contacts include the actin regulator α-actinin (2) and the human tumor suppressor scrib which regulates cell migration and polarity (3). |
存放说明 | -20C |
计算分子量 | 75 |
Western blot analysis of extracts from various cell types using LPP (8B3A110) Mouse mAb.使用LPP (8B3A110)小鼠单抗对多种细胞提取物进行western blot分析。 | |
Confocal immunofluorescent analysis of COS cells using LPP (8B3A11) Mouse mAb (green). Actin filaments have been labeled using DY-554 phalloidin (red). Blue pseudocolor = DRAQ5™ (fluorescent DNA dye).使用LPP (8B3A110)小鼠单抗(绿色)对COS细胞进行激光共聚焦免疫荧光分析。肌动蛋白丝使用DY-554 鬼笔环肽(红色)标记。蓝色假色= DRAQ5™(DNA荧光染料)。 | |
Immunohistochemical analysis of paraffin-embedded human small intestine using LPP (8B3A11) Mouse mAb.使用LPP (8B3A11) 小鼠单抗石蜡包埋的对人小肠组织进行免疫组化分析。 |