Lyric/Metadherin (2F11C3) Mouse mAb
货号：
9596S 基本售价：
3360.0 元 规格：
-
产品信息
概述| 货号 | 9596S |
| 反应种属 | Human/Monkey |
| 来源宿主 | Mouse |
| 应用 | W/IP |
| 目标/特异性 | Lyric/Metadherin (2F11C3) Mouse mAb detects endogenous levels of total lyric/metadherin protein. |
| 使用方法 | WB(1:1000)
IP (1:50) |
性能| 供应商 | CST |
| 背景 | Lyric/AEG-1 (Astrocyte Elevated Gene 1)/MTDH (Metadherin) was identified as a tight junction (TJ) protein based on its localization to TJ proteins in polarized epithelium (1).
Differential subcellular localization and overexpression of Lyric/AEG-1/MTDH has been seen in multiple human cancers. Lyric/AEG-1/MTDH is involved in signaling pathways related to various cellular functions including proliferation and apoptosis/survival, and its alteration in cancer is associated with poor prognosis (reviewed in 2). In breast cancer, increased Lyric/AEG-1/MTDH may confer increased chemoresistance as well as metastasis (3,4). Lyric/AEG-1/MTDH expression is important in signaling and disease progression of hepatocellular carcinoma (HCC) (5) and glioblastoma multiforme (GBM) (6). |
| 存放说明 | -20C |
| 计算分子量 | 65, 75 |
参考图片Western blot analysis of extracts from various cell lines and tissue using Lyric/Metadherin (2F11C3) Mouse mAb.使用Lyric/Metadherin (2F11C3) 鼠单抗对多种细胞和组织提取物进行western blot分析。 |
