| 货号 | 14685S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IF-IC |
| 使用方法 | WB(1:1000) IP (1:100) IF-IC (1:200) |
| 供应商 | CST |
| 背景 | Multidrug resistance-associated protein 1 (MRP1/ABCC1) is a member of the MRP subfamily of ATP-binding cassette (ABC) transporters (1). MRP1/ABCC1 protein functions as an organic anion transporter. It has a broad range of substrates, including antineoplastic or therapeutic agents and the glutathione (GSH) conjugates of these compounds. MRP1/ABCC1 also transports physiological substrates such as folates, GSH and GSH disulfide (GSSG) conjugates of steroids, leukotrienes, and prostaglandins (2,3). |
| 存放说明 | -20C |
| 计算分子量 | 170-220 |
Confocal immunofluorescent analysis of Hep G2 (left) and SK-MEL-2 (right) cells using MRP1/ABCC1 (D7O8N) Rabbit mAb (green). Actin filaments were labeled with DyLight™ 554 Phalloidin #13504 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). | |
Western blot analysis of extracts from A-549, PANC-1, and Hep G2 cells using MRP1/ABCC1 (D7O8N) Rabbit mAb. | |
Immunoprecipitation of MRP1/ABCC1 from Hep G2 cell extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or MRP1/ABCC1 (D7O8N) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using MRP1/ABCC1 (D7O8N) Rabbit mAb. | |
Western blot analysis of extracts from Hep G2 and SK-MEL-2 cells using MRP1/ABCC1 (D7O8N) Rabbit mAb (upper) and β-Actin (13E5) Rabbit mAb #4970 (lower). |
