| 货号 | 13018S |
| 反应种属 | Human/Mouse |
| 来源宿主 | Rabbit |
| 应用 | W/IP/IHC-P |
| 使用方法 | WB(1:1000) IP (1:50) IHC-P (1:800) |
| 供应商 | CST |
| 背景 | Despite their relatively small size (8-12 kDa) and uncomplicated architecture, S100 proteins regulate a variety of cellular processes such as cell growth and motility, cell cycle progression, transcription, and differentiation. To date, 25 members have been identified, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z, making it the largest group in the EF-hand, calcium-binding protein family. Interestingly, 14 S100 genes are clustered on human chromosome 1q21, a region of genomic instability. Research studies have demonstrated that significant correlation exists between aberrant S100 protein expression and cancer progression. S100 proteins primarily mediate immune responses in various tissue types but are also involved in neuronal development (1-4). |
| 存放说明 | -20C |
| 计算分子量 | 12 |
Western blot analysis of extracts from A172 and HeLa cells using S100A4 (D9F9D) Rabbit mAb. | |
Immunoprecipitation of S100A4 from A172 cell extracts using Rabbit (DA1E) mAb IgG XP® Isotype Control #3900 (lane 2) or S100A4 (D9F9D) Rabbit mAb (lane 3). Lane 1 is 10% input. Western blot analysis was performed using S100A4 (D9F9D) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human colon using S100A4 (D9F9D) Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right). | |
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma using S100A4 (D9F9D) Rabbit mAb. |
