| 货号 | 2093S |
| 反应种属 | Human |
| 来源宿主 | Rabbit |
| 应用 | W/IHC-P/F |
| 目标/特异性 | SCF (C19H6) Rabbit mAb detects endogenous levels of SCF by immunohistochemical staining and by flow cytometry. Western blotting detects recombinant SCF. |
| 使用方法 | WB(1:1000) IHC-P (1:50) F (1:100) |
| 供应商 | CST |
| 背景 | Stem cell factor (SCF) is a growth factor that is essential for hematopoiesis, melanogenesis and fertility. SCF is also known as mast cell growth factor (MCGF), steel factor (SLF), or kit ligand (KL) (1-3). SCF mediates its biological effects by binding to and activating c-Kit (4). SCF induces dimerization of c-Kit followed by trans-autophosphorylation of the cytoplasmic protein tyrosine kinase domain, leading to subsequent recruitment of signaling proteins, tyrosine phosphorylation of substrates and activation of multiple signaling pathways (5,6). SCF/c-Kit may take part in the growth control of human malignancies (7). |
| 存放说明 | -20C |
| 计算分子量 | 18 |
Flow cytometric analysis of U-87 MG cells using SCF (C19H6) Rabbit mAb (blue) compared to a nonspecific negative control antibody (red). 使用SCF (C19H6) Rabbit mAb (蓝色)兔单抗与非特异的阴性对照抗体（红色）对U-87 MG细胞进行流式细胞分析。 | |
Western blot analysis of recombinant SCF (5 ng) using SCF (C19H6) Rabbit mAb. 使用SCF (C19H6) Rabbit mAb兔单抗对重组SCF 蛋白(5 ng)进行Western blot 分析。 | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using SCF (C19H6) Rabbit mAb. 使用SCF (C19H6) Rabbit mAb兔单抗对石蜡包埋的人乳腺癌肿瘤样品进行免疫组化分析。 |
