| 货号 | 97958S |
| 反应种属 | Human |
| 来源宿主 | Rabbit IgG |
| 应用 | W/IHC-P |
| 使用方法 | IHC-P(1:200) |
| 供应商 | CST |
| 背景 | The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors (1). The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells (2). SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells (3,4). Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis (5,6). Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1α and SDF1β) that have different properties and biological activities (7). Additional isoforms of SDF1 have been reported (8,9). |
| 存放说明 | -20C |
| 计算分子量 | 10 |
Immunohistochemical analysis of paraffin-embedded human ovarian carcinoma using SDF1 (D8G6H) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma using SDF1 (D8G6H) Rabbit mAb. | |
Immunohistochemical analysis of paraffin-embedded human prostate carcinoma using SDF1 (D8G6H) Rabbit mAb. |
