Ms IL-18 Rcptr Bta NALE TC30-28E3 500ug
货号：
552422 基本售价：
14190.0 元 规格：
-
产品信息
概述| 货号 | 552422 |
| 描述 | The TC30-28E3 antibody specifically binds to the β subunit of the mouse Interleukin-18 Receptor complex (IL-18R β ). The mouse IL-18R complex is expressed by T cells stimulated with IL-12 alone or cultured with antigen and IL-12 to induce Th1 cells. IL-18R is constitutively expressed by NK cells. Resting mouse T cells and Th2 cells do not express detectable levels of IL-18R. The mouse IL-18R complex consists of the IL-18 α chain, also known as IL-1 Receptor related protein 1 (IL-1Rrp1 or IL-R5) and the IL-18R β chain also known as IL-1R accessory protein-like (IL-1RAcPL or IL-R7). The cell surface IL-18R α chain binds IL-18 with low affinity. However its interaction with the IL-18R β chain confers high affinity binding for the ligand. The IL-18R β chain is not involved in ligand binding but is responsible for the transduction of biological signals. The immunogen used to generate the TC30-28E3 hybridoma was sIL-1R7 fusion protein. |
| 别名 | IL-1RAcPL, IL-R7 |
| 同种亚型 | IgG2a,λ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | Neu |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse sIL-1R7 fusion protein |
| 标记 | NA/LE |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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| 存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
| 浓度 | 1.0 mg/ml |
