Ms CD51 NALE H9.2B8 500ug
货号：
553241 基本售价：
14040.0 元 规格：
-
产品信息
概述| 货号 | 553241 |
| 描述 | The H9.2B8 antibody reacts with the 140-kDa integrin α v chain (CD51). Heterodimers of CD51 with several integrin β chains function as receptors for extracellular matrix (ECM) proteins. CD51/CD61 ( αvβ 3 integrin, vitronectin receptor) mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31 (PECAM-1). It is expressed on activated T lymphocytes, polymorphonuclear granulocytes, blastocysts, and osteoclasts. We have been unable to detect CD51 on mouse platelets using either mAb H9.2B8 or RMV-7. CD51 also forms heterodimers with integrin β 1 (CD29) and β5,β 6, and α 8 chains. α v integrins have diverse functions in development and homeostasis. H9.2B8 antibody binds to an epitope of CD51 near or at the receptor-ligand binding site(s), as evidenced by its ability to synergistically participate in blocking of the adherence of vitronectin receptor-bearing cells to ECM proteins. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes. |
| 别名 | Integrin αv chain |
| 同种亚型 | IgG3,λ3 |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Ar hamster |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse C3H/HeN dendritic epidermal T cell line Y93A Cell Line |
| 标记 | NA/LE |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
|
| 存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
| 浓度 | 1.0 mg/ml |
