Hu CD86 NALE IT2.2 500ug
货号:
555662 基本售价:
8800.0 元 规格:
-
产品信息
概述货号 | 555662 |
描述 | IT2.2 recognizes a 75 kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells including lymphoid cells in germinal centers and Epstein-Barr virus transformed B-cell lines. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in costimulation of T cells in primary immune response. Competitive binding assays demonstrate that, while both IT2.2 and FUN-1 (anti-CD86, Cat. No. 555665) recognize the same molecule, they react with different epitopes. IT2.2 blocks costimulation activity of CD86 in functional studies and blocks binding of human CTLA-4-Ig fusion protein to B70 gene-transfected cells. |
别名 | B70/B7-2 |
同种亚型 | IgG2b,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC, FA |
性能供应商 | BD Pharmingen |
标记 | NA/LE |
存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
浓度 | 1.0 mg/ml |