A2B5 Pure 105/A2B5 100ug
货号:
563775 基本售价:
7410.0 元 规格:
-
产品信息
概述货号 | 563775 |
描述 | The 105/A2B5 monoclonal antibody binds to gangliosides in neural tissue in the retina, brain, spinal cord, and dorsal root ganglia. The antigenic gangliosides are found on the plasma membrane of neural cell bodies, but not axons or dendrites. Expression levels of the gangliosides that mAb 105/A2B5 binds to, including GT3 and its O-acetylated derivative, decrease during embryonic development of the brain. Thus, mAb 105/A2B5 may be used to monitor the maturation of brain tissue. A2B5 antigens have also been associated with numerous tumors, including glioblastoma multiforme tumor cells, pancreatic islet tumor cells, and rat insulinoma cells, and are thought to contribute to chemoresistance and increased tumor proliferation and recurrence. |
同种亚型 | Mouse BALB/c IgM |
反应种属 | Mouse (QC Testing) Human (Tested in Development) Rat, Chicken (Reported) |
性能供应商 | BD Pharmingen |
免疫原 | Chicken embryo retina Cells |
存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |