Bcl-w Pure 16H12 50ug
货号：
550559 基本售价：
7245.0 元 规格：
-
产品信息
概述| 货号 | 550559 |
| 描述 | The Bcl-2 family of proteins plays a pivotal role in determining the life and death of a cell. Members of the Bcl-2 family all possess at least one of four conserved Bcl-2 homology domains (BH1-BH4) which mediate protein-protein interactions. They can be divided into molecules that have either an anti-apoptotic or pro-apoptotic function. The ratio between these two groups of molecules can help determine whether a cell lives or dies. The majority of anti-apoptotic family members contain common BH1-BH4 domains and are most similar to Bcl-2. Bcl-w is a member of the antiapoptotic Bcl-2 group of proteins, including Bcl-x, Mcl-1, A1/Bfl-1, Boo/Diva, and Nr-13. Bcl-w was cloned from a mouse macrophage cell line and mouse brain. Bcl-w was found to be expressed in cells of myeloid origin, as well as many other tissues. The Bcl-w gene was inactivated in mice by homologous recombination and the resulting mice were viable and normal in appearance. Tissue histology demonstrated that male mice had reduced Sertoli and germ cells as well as having defective seminiferous tubules, resulting in infertility, while female mice had normal reproductive function. |
| 同种亚型 | IgG2a |
| 反应种属 | Mouse (QC Testing) Human (Reported) |
| 来源宿主 | Rat |
| 使用方法 | WB |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human Bcl-w full-length Recombinant Protein |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide and ≤0.09% Bronidox |
| 浓度 | 0.5 mg/ml |
