Bta PDGFR Tail Serum Poly 1036 0.1mL
货号：
554288 基本售价：
6438.0 元 规格：
-
产品信息
概述| 货号 | 554288 |
| 描述 | Platelet derived growth factor (PDGF) plays a role in regulating a number of biological processes including cellular proliferation and development through signal transduction. PDGF consists of homo- or heterodimers of two chains, A and B, which are encoded by two separate genes. The three possible combinations of the PDGF chains, AA, AB, and BB are all biologically active. The PDGF receptor (PDGFR) is a protein tyrosine kinase. Ligand binding to the PDGFR leads to tyrosine phosphorylation of numerous intracellular proteins, including the receptor itself. The PDGFR consists of two subunits, αandβ , which are encoded by two separate genes. The α subunit binds to both the A and B PDGF chains with high affinity, whereas the β subunit binds only to the B chain with high affinity. Ligand binding results in receptor dimerization, with the PDGF type (AA, AB, or BB) influencing the resulting PDGFR subunit composition ( αα,αβ , or ββ ). That is, PDGF-AA binds to αα receptors, PDGF-AB binds to ααandαβ receptors, and PDGF-BB binds to αα,αβ , or ββ receptors. This polyclonal antibody has been reported to recognize both mouse and human β PDGFR. The immature and mature forms of the β PDGFR subunit have been reported to be observed by SDS-PAGE migrating at 160 and 180 kDa, respectively. |
| 别名 | Platelet Derived Growth Factor Receptor β subunit |
| 反应种属 | Mouse (QC Testing) Human (Tested in Development) |
| 来源宿主 | Rabbit |
| 使用方法 | WB, IP |
性能| 供应商 | BD Pharmingen |
| 存放说明 | The polyclonal antibody was purified from antiserum by affinity chromatography.Store undiluted at 4°C.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
