Rat CD54 Pure 1A29 500ug
货号：
554967 基本售价：
6048.0 元 规格：
-
产品信息
概述| 货号 | 554967 |
| 描述 | The 1A29 antibody reacts with ICAM-1 (CD54), an 85 kDa surface glycoprotein expressed on vascular endothelium in lymphoid tissues, thymic stromal cells, peripheral blood monocytes, peritoneal macrophages and mast cells, dendritic cells, and weakly on peripheral lymphocytes and thymocytes. ICAM-1 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). Its expression is upregulated on activated lymphocytes and endothelial cells. 1A29 mAb inhibits PMA-induced aggregation of PHA-stimulated splenic blasts, as well as the adhesion of mitogen-stimulated blasts to HEV-derived endothelial cells and purified ICAM-1. It has also been reported that 1A29 antibody can inhibit leukocyte infiltration in in vivo systems, blocks induction of experimental allergic encephalomyelitis, and reduces NK-cell adhesion to tumor cells. The effects of in vivo administration of the 1A29 monoclonal antibody have been thoroughly investigated. |
| 别名 | ICAM-1 |
| 同种亚型 | IgG1,κ |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC, IHC(Fr), IP, IHC(Zn), IHC(F)* |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat HEV-Derived Cell Line Ax |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
