Hu CD16 NALE 3G8 500ug
货号：
555403 基本售价：
5740.0 元 规格：
-
产品信息
概述| 货号 | 555403 |
| 描述 | The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (Fc γ RIII), a human NK cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes. The 3G8 antibody is reported (Vossebeld et al ., 1997) to increase intracellular calcium levels in human neutrophils by interacting with both Fc γ RIIa and Fc γ RIIIb molecules. This antibody has also been reported to induce homotypic neutrophil aggregation. |
| 别名 | FcRIII; Fc-gamma RIII; FCG3; FCGR3; FCGRIII; FcγRIII; IGFR3 |
| 同种亚型 | IgG1,κ |
| 反应种属 | Human (QC Testing) Rhesus, Baboon, Cynomolgus (Tested in Development) |
| 来源宿主 | Mouse |
| 使用方法 | FC, FA |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Human polymorphonuclear leukocytes |
| 标记 | NA/LE |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
|
| 存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
| 浓度 | 1.0 mg/ml |
