Hu CD47 NALE B6H12 500ug
货号:
556043 基本售价:
5700.0 元 规格:
-
产品信息
概述货号 | 556043 |
描述 | The B6H12 monoclonal antibody specifically binds to CD47, a 42-52 kDa N-linked glycan protein. CD47 antigen, also known as integrin-associated protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells. The B6H12 antibody is capable of blocking phagocytosis of microparticles by peripheral blood granulocytes. It has also been reported to induce proliferation of CD3-activated T cells. |
别名 | IAP; CDw149; gp42; MER6; Neurophilin; OA3 ; Rh-related antigen |
同种亚型 | IgG1,κ |
反应种属 | Human (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC |
性能供应商 | BD Pharmingen |
免疫原 | Purified human placental RGD-binding proteins |
标记 | NA/LE |
存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
浓度 | 1.0 mg/ml |