Rat CD62L FITC HRL1 500ug
货号：
554963 基本售价：
5700.0 元 规格：
-
产品信息
概述| 货号 | 554963 |
| 描述 | The HRL1 antibody reacts with L-selectin (LECAM-1, CD62L), which is detected on a small percentage of thymocytes and on most neutrophils and peripheral lymphocytes. CD62L is a 62-kDa (on neutrophils) or 65-kDa (on lymphocytes) receptor, with lectin-like and epidermal growth factor-like domains, which binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. This member of the selectin adhesion molecule family appears to be required for lymphocyte homing to peripheral lymph nodes and to contribute to neutrophil emigration at inflammatory sites. L-selectin is rapidly shed from lymphocytes and neutrophils upon cell activation. In the mouse, the level of CD62L expression distinguishes naive CD4+T cells from effector/memory T helper cells. HRL1 antibody inhibits the ligand-binding activity of Lselectin in in vitro assays and slows in vivo leukocyte rolling on microvascular endothelium. |
| 别名 | L-selectin, LECAM-1 |
| 同种亚型 | IgG2,λ1 |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Ar hamster |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat LECAM-1 human IgG1 fusion protein |
| 标记 | FITC |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
