Rat CD2 Pure OX-34 500ug
货号：
554826 基本售价：
5320.0 元 规格：
-
产品信息
概述| 货号 | 554826 |
| 描述 | The OX-34 antibody reacts with CD2 (LFA-2), a member of the immunoglobulin superfamily. In the rat, CD2 is expressed on thymocytes, T lymphocytes in spleen and lymph node, dendritic epidermal T cells, splenic macrophages, and NK cells, but not on B cells, most intestinal intraepithelial lymphocytes, or peritoneal and liver macrophages. CD2 can associate with the T-cell receptor complex, and it may function in both intercellular adhesion and signal transduction. In the rat, CD48 and CD59 have been identified as ligands for CD2. OX-34 mAb binds to the extracellular portion of CD2, and it blocks the binding of CD2 to CD48. While OX-34 antibody does not activate T cells, it partially blocks activation by immobilized mAbs to CD3 (clone G4.18) and αβ T-cell receptor (clone R73), and it partially inhibits allogeneic mixed lymphocyte reactions. Moreover, in vivo administration of OX-34 antibody depletes peripheral T cells and prevents allograft rejection. |
| 别名 | LFA-2 |
| 同种亚型 | IgG2a,κ |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | FC, IHC(F), IHC(Fr), IP |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Rat T blasts from mixed lymphocyte reactions |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
