Rat Tau Pure TAU-5 100ug
货号：
556319 基本售价：
5092.0 元 规格：
-
产品信息
概述| 货号 | 556319 |
| 描述 | Tau proteins are microtuble-associated proteins (MAPs) that are thought to function by stabilizing microtubles. They comprise a family of multiple polypeptides that originate from one gene. Alternate splicing of Tau mRNA and differential phosphorylation contribute to the heterogeneity of Tau. Typically, Tau proteins migrate between ~ 45-70 kDa with isoelectric points ranging from 6.5-8.0. Tau expression is widespread in the brain and is found in most cell types within the mammalian central nervous system. Tau has a complex biochemical nature that is partly due to its many isoforms. The number and molecular weights of Tau forms changes during brain development. Additionally, the molecular wieghts and forms of Tau proteins at a given point of development vary between species. Antibodies directed against different epitopes have been used to distinguish between Tau forms. The monoclonal antibody TAU-5 recognizes a phosphorylation-independent epitope on Tau proteins. The reduced molecular weight of Tau proteins may range between 45 kDa to 95 kDa. The TAU-5 antibody reacts with a phosphorylation-independent epitope in the middle of tau. It recognizes both the phosphorylated and non-phosphorylated form of Tau. The antibody has been characterized in rat tissue. |
| 同种亚型 | IgG1 |
| 反应种属 | Rat (QC Testing) |
| 来源宿主 | Mouse |
| 使用方法 | WB, IHC(F) |
性能| 供应商 | BD Pharmingen |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
