Ms CD162 NALE 4RA10 500ug
货号：
557787 基本售价：
4970.0 元 规格：
-
产品信息
概述| 货号 | 557787 |
| 描述 | The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selplgene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, SelplmRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L. |
| 别名 | PSGL-1 |
| 同种亚型 | IgG1,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | Block, FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | PSGL-1 human IgG1 fusion protein |
| 标记 | NA/LE |
| 存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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| 存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
| 浓度 | 1.0 mg/ml |
