Rat CD161a NKR-P1A Pure 10/78 500ug
货号:
555006 基本售价:
4896.0 元 规格:
-
产品信息
概述货号 | 555006 |
描述 | The 10/78 antibody reacts with NKR-P1A, a 60-kDa homodimer expressed on all natural killer (NK) cells and a small subset of T lymphocytes. The 10/78 antibody competes with the previously described 3.2.3 antibody for binding to the antigen. NKR-P1A is a type-II integral membrane protein with an extracellular C-type lectin domain, which is an NK cell-activating receptor specific for tumor target cells. Many rat dendritic cells have been shown to express NKR-P1A, and a subpopulation of these cells has cytotoxic activity. NKR-P1A has also been detected at low levels on peripheral blood monocytes, and its expression is upregulated in IFN-γ-activated monocytes, specifically in a subpopulation of large monocytes with phagocytic capacity. Furthermore, activated peripheral blood neutrophils may express a low level of NKR-P1A. In the mouse and rat, three members of the NKR-P1gene family have been identified; but in the human gene family, a single NKR-P1 homologue has been discovered and designated Cd161. |
别名 | CD161/Cd161; CD161a, Klrb1a, Nkrp1a/NKR-P1A; CD161b, Klrb1b, Nkrp1b/NKR-P1B |
同种亚型 | IgG1,κ |
反应种属 | Rat (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC, IHC(Fr), IP, IHC(Zn) |
性能供应商 | BD Pharmingen |
免疫原 | Not reported |
存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.5 mg/ml |