Rat CD3 NALE G4.18 500ug
货号:
554829 基本售价:
4592.0 元 规格:
-
产品信息
概述货号 | 554829 |
描述 | The G4.18 antibody reacts with the T-cell receptor-associated CD3 cell-surface antigen found on thymocytes, peripheral T lymphocytes, and dendritic epidermal T cells. It has been reported that CD3 expression is down-regulated within 24 hours in concanavalin A-stimulated rat T cells, and soluble mAb inhibits the allogeneic mixed-lymphocyte proliferative response and cell-mediated cytotoxicity to allogeneic target cells. In vivo treatment with G4.18 mAb prevents cardiac and skin allograft rejection, resulting in donor-specific tolerance. Pre-incubation of splenocytes with the alternate anti-rat CD3 monoclonal antibody, 1F4 (Cat. No. 556970), blocks staining with mAb G4.18. |
同种亚型 | IgG3,κ |
反应种属 | Rat (QC Testing) |
来源宿主 | Mouse |
使用方法 | FC, Block, Cost, Cyt |
性能供应商 | BD Pharmingen |
免疫原 | PHA-stimulated rat lymph node and spleen cells |
标记 | NA/LE |
存放说明 | Store undiluted at 4°C.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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存储溶液 | No azide/low endotoxin: Aqueous buffered solution containing protein stabilizer, no preservative, 0.2µm sterile filtered. Endotoxin level is ≤0.01 EU/µg (≤0.001 ng/µg) of protein as determined by the LAL assay. |
浓度 | 1.0 mg/ml |